Analytical Data
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Gene name
PLIN3
- Application
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Alternative Names
PLIN3；M6PRBP1；TIP47；Perilipin-3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60664
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Expression Region
2-434aa
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AA Sequence
SADGAEADG STQVTVEEPV QQPSVVDRVA SMPLISSTCD MVSAAYASTK ESYPHIKTVC DAAEKGVRTL TAAAVSGAQP ILSKLEPQIA SASEYAHRGL DKLEENLPIL QQPTEKVLAD TKELVSSKVS GAQEMVSSAK DTVATQLSEA VDATRGAVQS GVDKTKSVVT GGVQSVMGSR LGQMVLSGVD TVLGKSEEWA DNHLPLTDAE LARIATSLDG FDVASVQQQR QEQSYFVRLG SLSERLRQHA YEHSLGKLRA TKQRAQEALL QLSQVLSLME TVKQGVDQKL VEGQEKLHQM WLSWNQKQLQ GPEKEPPKPE QVESRALTMF RDIAQQLQAT CTSLGSSIQG LPTNVKDQVQ QARRQVEDLQ ATFSSIHSFQ DLSSSILAQS RERVASAREA LDHMVEYVAQ NTPVTWLVGP FAPGITEKAP EEKK
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLIN3, also known as perilipin 3, is a member of the perilipin family of proteins, which play crucial roles in lipid metabolism and the regulation of intracellular lipid storage. Prior studies have demonstrated that PLIN3 is involved in the protection of lipid droplets and participates in the dynamic process of lipid mobilization, acting as a stabilizer and regulating the access of lipases. Dysregulation of PLIN3 has been linked to various metabolic disorders, including obesity, insulin resistance, and cardiovascular diseases, making it a potential target for therapeutic interventions. Recent research has focused on generating recombinant PLIN3 protein to study its structure-function relationship, explore its role in lipolysis and adipocyte physiology, and identify potential interaction partners. Through techniques such as recombinant DNA technology and in vitro functional assays, scientists aim to elucidate the molecular mechanisms by which PLIN3 contributes to lipid homeostasis and its implications in metabolic diseases. Understanding the biology of PLIN3 provides insight into novel strategies for the treatment and prevention of lipid-related disorders, potentially leading to the development of innovative therapeutic approaches targeting lipid metabolism. Thus, investigating the properties and functions of PLIN3 through recombinant protein studies is a burgeoning field with significant implications for improving metabolic health.
