Analytical Data
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基因名
AMELX
- Application
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别名
AMELX；AMG；AMGX；Amelogenin. X isoform
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51646
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表达区间
17-191aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMPLPPHP GHPGYINFSY EVLTPLKWYQ SIRPPYPSYG YEPMGGWLHH QIIPVLSQQH PPTHTLQPHH HIPVVPAQQP VIPQQPMMPV PGQHSMTPIQ HHQPNLPPPA QQPYQPQPVQ PQPHQPMQPQ PPVHPMQPLP PQPPLPPMFP MQPLPPMLPD LTLEAWPSTD KTKREEVD
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分子量
22 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AMELX, or Amelogenin X, is a key protein involved in the enamel formation of teeth and is a crucial component of the extracellular matrix during odontogenesis. Research into AMELX has garnered significant attention due to its role in the development of dental enamel and its implications in dental disorders. Mutations or deficiencies in the AMELX gene can lead to various forms of amelogenesis imperfecta, a condition characterized by defective enamel formation, resulting in increased susceptibility to caries and other dental issues. The study of recombinant AMELX protein is important for understanding its structural and functional properties, as well as its interactions with other proteins involved in mineralization processes. Additionally, recombinant AMELX can be utilized in tissue engineering and regenerative dentistry, offering potential therapeutic applications for enamel repair and regeneration. By investigating the mechanisms of AMELX's action and its role in enamel biomineralization, researchers aim to develop innovative strategies for preventing and treating enamel-related diseases and improving overall dental health. Furthermore, this research holds promise for advancing our understanding of tooth development and the molecular basis of dental diseases, paving the way for future innovations in dental care and restorative techniques.
