Analytical Data
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Gene name
AMELX
- Application
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Alternative Names
AMELX；AMG；AMGX；Amelogenin. X isoform
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P51646
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Expression Region
17-191aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMPLPPHP GHPGYINFSY EVLTPLKWYQ SIRPPYPSYG YEPMGGWLHH QIIPVLSQQH PPTHTLQPHH HIPVVPAQQP VIPQQPMMPV PGQHSMTPIQ HHQPNLPPPA QQPYQPQPVQ PQPHQPMQPQ PPVHPMQPLP PQPPLPPMFP MQPLPPMLPD LTLEAWPSTD KTKREEVD
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Molecular Weight
22 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AMELX, or Amelogenin X, is a key protein involved in the enamel formation of teeth and is a crucial component of the extracellular matrix during odontogenesis. Research into AMELX has garnered significant attention due to its role in the development of dental enamel and its implications in dental disorders. Mutations or deficiencies in the AMELX gene can lead to various forms of amelogenesis imperfecta, a condition characterized by defective enamel formation, resulting in increased susceptibility to caries and other dental issues. The study of recombinant AMELX protein is important for understanding its structural and functional properties, as well as its interactions with other proteins involved in mineralization processes. Additionally, recombinant AMELX can be utilized in tissue engineering and regenerative dentistry, offering potential therapeutic applications for enamel repair and regeneration. By investigating the mechanisms of AMELX's action and its role in enamel biomineralization, researchers aim to develop innovative strategies for preventing and treating enamel-related diseases and improving overall dental health. Furthermore, this research holds promise for advancing our understanding of tooth development and the molecular basis of dental diseases, paving the way for future innovations in dental care and restorative techniques.
