Analytical Data
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Gene name
AMD1
- Application
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Alternative Names
AMD1；AMP deaminase 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P17707
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Expression Region
68-334aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMSSMFV SKRRFILKTC GTTLLLKALV PLLKLARDYS GFDSIQSFFY SRKNFMKPSH QGYPHRNFQE EIEFLNAIFP NGAAYCMGRM NSDCWYLYTL DFPESRVISQ PDQTLEILMS ELDPAVMDQF YMKDGVTAKD VTRESGIRDL IPGSVIDATM FNPCGYSMNG MKSDGTYWTI HITPEPEFSY VSFETNLSQT SYDDLIRKVV EVFKPGKFVT TLFVNQSSKC RTVLASPQKI EGFKRLDCQS AMFNDYNFVF TSFAKKQQQQ QS
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Molecular Weight
33 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of AMD1 recombinant proteins is significant due to their crucial role in cellular metabolism, particularly in the regulation of polyamine biosynthesis. AMD1, or Adenosine Monophosphate Deaminase 1, is an enzyme that catalyzes the conversion of adenosine monophosphate (AMP) to inosine monophosphate (IMP), a critical precursor in the synthesis of nucleotides. Alterations in the activity of AMD1 have been linked to various pathological conditions, including cancer, where aberrant polyamine metabolism can promote tumor growth and development. As researchers strive to understand the molecular mechanisms behind these diseases, AMD1 has emerged as a potential therapeutic target. Recombinant protein technology allows for the expression and purification of AMD1, facilitating detailed studies into its structure, function, and interactions with other cellular components. By characterizing AMD1 through recombinant approaches, scientists aim to uncover its regulatory pathways and potential as a biomarker or target in therapeutic interventions. The insights gained from these studies can lead to novel strategies for cancer treatment and better understanding of metabolic disorders, highlighting the importance of AMD1 in both health and disease.
