Cat: PA1000-11DB

Recombinant Human YWHAQ Protein,His

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Analytical Data

  • 基因名

    YWHAQ

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    YWHAq;14-3-3 Protein theta

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    C-his

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P27348

  • 表达区间

    1-245aa

  • 氨基酸序列

    MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN

  • 分子量

    54.8kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

YWHAQ, also known as 14-3-3σ, is a member of the 14-3-3 protein family, which is involved in various cellular processes including signal transduction, cell cycle regulation, and apoptosis. The 14-3-3 proteins are highly conserved and are known to interact with a multitude of partner proteins, thereby modulating their function and stability. Research on YWHAQ has garnered attention due to its critical role in cancer biology, where it is often implicated in tumor suppression and the regulation of oncogenic pathways. Understanding the mechanisms by which YWHAQ operates could provide insights into its potential as a therapeutic target or biomarker for cancer diagnosis and treatment. Additionally, studies have shown that alterations in YWHAQ expression levels can significantly impact cell proliferation and survival, highlighting its importance in maintaining cellular homeostasis. Given the complex nature of its interactions and functions, the recombinant production of YWHAQ protein is of great interest, facilitating the exploration of its biochemical properties and functional roles in vitro. This research is vital to elucidating the molecular underpinnings of YWHAQ and its broader implications in health and disease, positioning it as a significant focus in the fields of molecular biology and cancer research. By developing advanced methodologies for the expression and purification of YWHAQ, scientists aim to enhance our understanding of its interactions with key signaling pathways and its overall contribution to cellular dynamics.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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