Analytical Data
-
Gene name
ELOVL1
- Application
-
Alternative Names
ELOVL1；SSC1；Very long chain fatty acid elongase 1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9BW60
-
Expression Region
1-279aa
-
AA Sequence
MEAVVNLYQEVMKHADPRIQGYPLMGSPLLMTSILLTYVYFVLSLGPRIMANRKPFQLRGFMIVYNFSLVALSLYIVYEFLMSGWLSTYTWRCDPVDYSNSPEALRMVRVAWLFLFSKFIELMDTVIFILRKKDGQVTFLHVFHHSVLPWSWWWGVKIAPGGMGSFHAMINSSVHVIMYLYYGLSAFGPVAQPYLWWKKHMTAIQLIQFVLVSLHISQYYFMSSCNYQYPVIIHLIWMYGTIFFMLFSNFWYHSYTKGKRLPRALQQNGAPGIAKVKAN
-
Molecular Weight
32.6 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ELOVL1, or Elongation of Very Long Chain Fatty Acids Protein 1, is an enzyme belonging to the ELOVL family responsible for the elongation of long-chain fatty acids, specifically those containing 18 to 26 carbon atoms. Research into ELOVL1 has gained significant importance due to its critical role in lipid metabolism and the synthesis of essential fatty acids, which are vital for maintaining cellular membrane integrity and overall human health. Mutations in the ELOVL1 gene have been linked to various conditions, including skin disorders and neurological diseases, highlighting its potential impact on metabolic pathways and physiological processes. Recent studies have focused on the recombinant expression of ELOVL1 to better understand its enzymatic function, substrate specificity, and interaction with other metabolic factors. By producing recombinant ELOVL1 in various expression systems, researchers aim to elucidate its role in fatty acid elongation and its potential therapeutic implications, particularly in disorders caused by fatty acid imbalances. Overall, ELOVL1 serves as a promising target for further investigations into its function and the development of novel treatments for metabolic and genetic diseases related to lipid abnormalities.
