Analytical Data
-
基因名
cmk
- Application
-
别名
Cytidine monophosphate kinase ;CMP kinaseProtein MssAp25
-
种属
Escherichia coli
-
表达系统
E. coli
-
标签
N- His-SUMO
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P0A6I0
-
表达区间
1-227aa
-
分子量
40.7 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of CMK (Calmodulin-Dependent Protein Kinase) recombinant proteins stems from the increasing recognition of their crucial roles in various cellular processes, including signal transduction, cellular proliferation, and apoptosis. CMKs are a family of protein kinases that are activated by the calcium-binding protein calmodulin, which acts as a key mediator in calcium-dependent signaling pathways. Understanding CMK's molecular mechanisms is vital due to their implications in numerous physiological functions and potential pathophysiological conditions, such as cancer and cardiovascular diseases. The recombinant production of CMK proteins allows researchers to investigate their structure-function relationships, enzymatic activity, and regulation in detail. Additionally, recombinant CMK proteins provide a valuable tool for high-throughput screening of potential therapeutics and for exploring their interactions with various substrates and inhibitors. This research is further propelled by advancements in genetic engineering techniques, which have improved the efficiency of producing functional CMK isoforms. By elucidating CMK signaling pathways, scientists aim to develop targeted strategies for modulating these pathways, ultimately paving the way for novel therapeutic approaches in treating diseases associated with dysfunctional calcium signaling.
