Analytical Data
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Gene name
cmk
- Application
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Alternative Names
Cytidine monophosphate kinase ;CMP kinaseProtein MssAp25
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Species
Escherichia coli
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P0A6I0
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Expression Region
1-227aa
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Molecular Weight
40.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of CMK (Calmodulin-Dependent Protein Kinase) recombinant proteins stems from the increasing recognition of their crucial roles in various cellular processes, including signal transduction, cellular proliferation, and apoptosis. CMKs are a family of protein kinases that are activated by the calcium-binding protein calmodulin, which acts as a key mediator in calcium-dependent signaling pathways. Understanding CMK's molecular mechanisms is vital due to their implications in numerous physiological functions and potential pathophysiological conditions, such as cancer and cardiovascular diseases. The recombinant production of CMK proteins allows researchers to investigate their structure-function relationships, enzymatic activity, and regulation in detail. Additionally, recombinant CMK proteins provide a valuable tool for high-throughput screening of potential therapeutics and for exploring their interactions with various substrates and inhibitors. This research is further propelled by advancements in genetic engineering techniques, which have improved the efficiency of producing functional CMK isoforms. By elucidating CMK signaling pathways, scientists aim to develop targeted strategies for modulating these pathways, ultimately paving the way for novel therapeutic approaches in treating diseases associated with dysfunctional calcium signaling.
