Analytical Data
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基因名
mpt51
- Application
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别名
mpt51; fbpC1; fbpD; mpb51; MT3910; MPT51/MPB51 antigen
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种属
Mycobacterium tuberculosis
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P9WQN6
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表达区间
27-299aa
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分子量
44.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The MPT51 protein, derived from Mycobacterium tuberculosis, has gained significant interest in immunological and vaccine research due to its potential role in tuberculosis (TB) pathogenesis. This protein is part of the mammalian protein translation (MPT) family, which is believed to have significant effects on the host immune response. Studies have shown that MPT51 can modulate immune cell functions, such as activating macrophages and influencing T-cell responses, which are critical in combating TB. Given that TB remains one of the leading causes of infectious disease-related mortality worldwide, understanding the function and structure of MPT51 is crucial for developing novel diagnostic tools and effective vaccines. Research efforts have focused on elucidating the biochemical properties of MPT51, its interaction with host immune components, and its potential to serve as a biomarker for TB infection. The recombinant production of MPT51 has enabled researchers to explore its immunogenicity and therapeutic applications further, including its possible use in immunization strategies. By investigating the molecular mechanisms through which MPT51 affects host immunity, researchers aim to identify new avenues for TB treatment and prevention, ultimately contributing to global health initiatives aimed at eradicating this devastating disease.
