Analytical Data
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Gene name
KIR2DL5B
- Application
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Alternative Names
(CD158 antigen-like family member F2)(Killer cell immunoglobulin-like receptor 2DLX)(CD antigen CD158f2)
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NHK3
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Expression Region
22-238aa
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Molecular Weight
30.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KIR2DL5B is a member of the killer cell immunoglobulin-like receptor (KIR) family, which plays a significant role in regulating the immune response, particularly in natural killer (NK) cells. KIRs interact with major histocompatibility complex (MHC) molecules, allowing NK cells to distinguish between healthy and infected or transformed cells. The KIR2DL5B receptor is of particular interest due to its unique expression pattern and potential implications in various diseases, including infections, cancer, and autoimmune disorders. Research has indicated that certain KIR genes, including KIR2DL5B, may influence susceptibility to diseases as well as the outcomes of transplantation. Furthermore, understanding the structural and functional characteristics of KIR2DL5B can provide insights into its role in immune regulation. The recombination of KIR2DL5B into protein constructs enables detailed studies of its function, interactions, and signaling pathways. This research could pave the way for novel immunotherapeutic strategies aimed at enhancing NK cell activity against tumors and viral infections, making KIR2DL5B an important focus in immunological studies.
