Analytical Data
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基因名
Mcpt1
- Application
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别名
Chymase (Chymotrypsin-like protease) (CLIP protein) (Mast cell protease I) (rMCP-I) (rMCP-1)
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种属
Rat
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表达系统
E. coli
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标签
N- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P09650
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表达区间
21-260aa
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分子量
28.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Mcpt1 (Mast Cell Protease 1) is a serine protease primarily expressed in mast cells and plays a pivotal role in immune responses and tissue homeostasis. The study of Mcpt1 has gained traction due to its involvement in various physiological and pathological processes, including allergic reactions, asthma, and other inflammatory disorders. As a key effector molecule released during mast cell degranulation, Mcpt1 contributes to the degradation of extracellular matrix components, modulation of immune cell function, and regulation of inflammatory responses. Understanding the mechanisms underlying Mcpt1's activity can provide insights into its dual role as both a mediator and modulator of inflammation. Recent advances in molecular biology techniques have allowed researchers to investigate the structural and functional characteristics of Mcpt1, leading to potential therapeutic applications in managing mast cell-related diseases. By targeting Mcpt1 or its signaling pathways, innovative strategies can be developed to mitigate excessive inflammation and improve disease outcomes, highlighting the significance of Mcpt1 in both basic and applied research.
