Analytical Data
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基因名
PCBP2
- Application
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别名
Alpha-CP2;Heterogeneous nuclear ribonucleoprotein E2;hnRNP E2
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15366
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表达区间
1-365aa
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分子量
46.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PCBP2 (poly(rC)binding protein 2) is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, playing a crucial role in post-transcriptional regulation of gene expression. It is known to bind poly(C) RNA sequences and is involved in various cellular processes such as mRNA stability, splicing, and translation. The study of PCBP2 has gained significant attention due to its implications in several physiological and pathological conditions, including cancer, viral infections, and neurodegenerative diseases. For instance, PCBP2 has been implicated in enhancing the translation of specific mRNAs, which can contribute to tumor growth and progression. Additionally, it can serve as a cofactor for viral RNA replication, making it a potential target for antiviral therapy. As a result, researchers are increasingly focused on characterizing the structure and function of recombinant PCBP2 to understand its interaction networks and regulatory mechanisms. By producing and studying recombinant forms of PCBP2, scientists aim to elucidate its role in cellular processes and its potential as a biomarker or therapeutic target in disease. This research not only enhances our understanding of basic cellular function but also opens avenues for novel therapeutic strategies leveraging PCBP2's unique properties.












