Cat: IPD-X41225

Recombinant Human DDX3Y Protein (Baculovirus),His & Myc

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Analytical Data

  • Gene name

    DDX3Y

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    DEAD box protein 3, Y-chromosomal

  • Species

    Human

  • Source

    Baculovirus

  • Tag

    N- His & C- Myc

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O15523

  • Expression Region

    2-660aa

  • Molecular Weight

    76.9

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

DDX3Y is a member of the DEAD-box helicase family, which plays a crucial role in RNA metabolism, including processes such as translation and splicing. It is located on the Y chromosome and is expressed primarily in male germ cells, contributing to spermatogenesis and fertility. Research into DDX3Y has gained traction due to its involvement in various biological processes and potential implications in male infertility. Furthermore, aberrations in DDX3Y expression have been linked to the development of certain cancers and other diseases, suggesting its role as a potential biomarker or therapeutic target. The production of recombinant DDX3Y protein allows for detailed studies of its structure and function, facilitating insights into its mechanisms of action. This research is pivotal for understanding the pathological roles of DDX3Y in both developmental and disease contexts, paving the way for novel diagnostic and therapeutic approaches in male reproductive health and cancer biology.

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