Cat: IPD-X40112

Recombinant Pseudomonas aeruginosa pscF Protein ,His & Myc

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Analytical Data

  • 基因名

    pscF

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Pseudomonas secretion protein F

  • 种属

    Pseudomonas aeruginosa

  • 表达系统

    E. coli

  • 标签

    N- His & C- Myc

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P95434

  • 表达区间

    2-85aa

  • 分子量

    16.6 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

The recombinant protein PSCF (Pulmonary Surfactant-Associated Protein F) has garnered significant attention in recent years due to its crucial role in lung function and surfactant homeostasis. PSCF is part of a family of proteins that are essential for reducing surface tension in the alveoli, which prevents lung collapse and facilitates efficient gas exchange. Its dysfunction is associated with various respiratory diseases, including Acute Respiratory Distress Syndrome (ARDS) and neonatal respiratory distress syndrome. Research into PSCF aims to better understand its structural and functional properties, along with its interactions with other surfactant proteins and lipids. Studies have focused on the recombinant expression of PSCF in various systems to produce sufficient quantities for biochemical and functional assays. Additionally, investigations are being conducted to explore the therapeutic potential of PSCF in treating pulmonary disorders, leveraging its properties to enhance surfactant replacement therapies. This research is further supported by advancements in genetic engineering techniques, allowing for the design of PSCF variants with improved stability and activity. Overall, the study of PSCF and its recombinant forms is pivotal for developing novel therapeutic strategies to address pulmonary diseases, ultimately contributing to improved patient outcomes and insights into the underlying mechanisms of surfactant biology.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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