Analytical Data
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基因名
FGF-14
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简介
FGF-14 Protein likely plays a crucial role in the development and functioning of the nervous system, contributing to intricate processes underlying neural structure and activity. Its interaction with SCN8A suggests potential involvement in modulating this sodium channel's activity, emphasizing its intricate role in neurophysiology. FGF-14 Protein, Human (isoform 1B) is the recombinant human-derived FGF-14 protein, expressed by E. coli , with tag free.
- Application
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别名
Fibroblast growth factor 14; FHF-4; FGF14
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种属
Human
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表达系统
E. coli
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92915-2
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表达区间
K64-T252
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蛋白长度
Partial
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分子量
18kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Fibroblast growth factor 14 (FGF-14) is a member of the fibroblast growth factor family, which includes various proteins involved in critical biological processes such as cell proliferation, differentiation, and survival. Notably, FGF-14 has garnered attention due to its unique expression pattern in the brain, particularly in regions associated with neuronal development and plasticity. Its role in synaptic function and modulation of ion channels suggests that FGF-14 may be integral to neurological processes, including learning and memory. Emerging studies have indicated that mutations or dysregulation of FGF-14 could be linked to various neurological disorders, making it a potential therapeutic target. The recombinant protein production of FGF-14 allows researchers to investigate its structure-function relationship, engage in functional assays, and explore its interactions with cellular receptors. Understanding FGF-14's mechanism of action at the molecular level could pave the way for novel interventions in neurodegenerative diseases and other conditions where FGF-14 is implicated. As a result, the research surrounding FGF-14 recombinant protein contributes significantly to the broader field of neuroscience, underscoring the need for more in-depth studies to unravel its complex biological roles.
