Analytical Data
-
Gene name
MML3
- Application
-
Alternative Names
/
-
Species
Gossypium hirsutum
-
Source
E. coli
-
Tag
N- His-GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
A0A0K2G548
-
Expression Region
1-367aa
-
Molecular Weight
71 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MML3 (MAML3) is a member of the Mastermind-like (MAML) family of proteins that plays a crucial role in the Notch signaling pathway, which is essential for cellular differentiation and developmental processes. The Notch pathway is highly conserved across species and is involved in various biological functions, including cell fate determination, proliferation, and apoptosis. Dysregulation of Notch signaling has been implicated in several diseases, notably cancer, where it often contributes to tumorigenesis and metastasis. As a transcriptional coactivator, MML3 interacts with Notch receptors and facilitates the transcription of target genes, impacting various cellular processes. Recent studies have focused on elucidating the molecular mechanisms of MML3 function, its interactions with other signaling pathways, and its role in the context of human diseases. The recombinant expression of MML3 protein allows researchers to investigate its biochemical properties, structural characteristics, and functional significance, providing deeper insight into its contribution to Notch-related signaling pathways. Understanding MML3 not only adds to the knowledge of developmental biology but also presents potential therapeutic targets for diseases associated with aberrant Notch signaling. As a result, MML3 has emerged as an important subject of research in the fields of molecular biology, oncology, and regenerative medicine, highlighting its significance in understanding complex cellular networks and the development of innovative treatment strategies.
