Analytical Data
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Gene name
IGSF11
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简介
IGSF11 (Immunoglobulin superfamily member 11) operates as a cell adhesion molecule by engaging in homophilic interactions, thereby facilitating cell-to-cell adhesion. Additionally, IGSF11 is implicated in the stimulation of cell growth, suggesting a role in cellular proliferation and potentially contributing to regulatory pathways involved in cellular development and maintenance. IGSF11 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGSF11 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Biological Activity
VISTA immobilized on CM5 Chip can bind IGSF11 with an affinity constant of 160.8 μM as determined in SPR assay. VISTA immobilized on CM5 Chip can bind IGSF11 with an affinity constant of 160.8 μM as determined in SPR assay.
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Alternative Names
IgSF11; Bt-IGSF; Bt IGSF; BtIGSF; VSIG3; CXADRL1; CT119
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Species
Mouse
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Source
HEK293
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Tag
C-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
P0C673
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Expression Region
L23-V240
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Protein Length
Extracellular Domain
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Molecular Weight
32-42 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IGSF11 (Immunoglobulin Superfamily Member 11) is a member of the immunoglobulin superfamily known for its role in cellular adhesion and signaling processes. Initial research indicated that IGSF11 is predominantly expressed in immune tissues, suggesting its potential involvement in immune responses and cell-to-cell interactions. Recent studies have identified its significance in various biological processes, including the regulation of T-cell activation and differentiation, pointing to its potential role in autoimmune diseases and cancer. The generation of recombinant IGSF11 protein has become a focal point in research to elucidate its functional properties and interactions. By producing IGSF11 in a recombinant form, researchers can investigate its structure-function relationships, binding affinities, and how it influences immune cell behavior. This research may lead to a deeper understanding of IGSF11’s contributions to immune regulation and its implications in pathological conditions. Furthermore, recombinant IGSF11 could serve as a tool for therapeutic interventions or as a biomarker for specific diseases. As the field of immunology continues to advance, the study of recombinant IGSF11 protein stands to offer valuable insights into its potential roles in health and disease.
