Analytical Data
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Gene name
Pld3
- Application
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Alternative Names
Choline phosphatase 3 (Phosphatidylcholine-hydrolyzing phospholipase D3) (Schwannoma-associated protein 9) (SAM-9) (Sam9) (PLD 3)
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Species
Mouse
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O35405
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Expression Region
1-488aa
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Molecular Weight
58.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLD3 (phospholipase D family member 3) is a member of the phospholipase D family, which plays a crucial role in lipid metabolism and cell signaling. Recent studies have highlighted its potential involvement in neurodegenerative diseases, particularly Alzheimer’s disease, where mutations in the PLD3 gene have been associated with altered risk levels. Researchers have become increasingly interested in understanding the structure and function of PLD3, as well as its role in the pathophysiology of these diseases. The production of recombinant PLD3 protein allows for detailed biochemical and biophysical analyses, enabling scientists to investigate the enzyme's activity, substrate specificity, and interaction with other cellular components. This research is pivotal in elucidating the mechanisms underlying PLD3's involvement in neurodegeneration and could pave the way for the development of therapeutic strategies targeting PLD3 to mitigate disease progression. Furthermore, recombinant PLD3 can serve as a valuable tool for high-throughput screening of small molecules that may modulate its activity, thereby contributing to the discovery of novel interventions in neurodegenerative diseases.
