Analytical Data
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Gene name
AG-2
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简介
AG-2 protein is a member of the protein disulfide isomerase family and is predicted to bind to dystroglycan, epidermal growth factor receptor, and the same proteins.It plays a role in digestive tract morphogenesis, mucus secretion, and developmental growth regulation.AG-2 Protein, Mouse (His) is the recombinant mouse-derived AG-2 protein, expressed by E.coli , with C-His labeled tag.
- Application
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Alternative Names
Anterior gradient protein 2 homolog; AG-2; AG2; hAG-2; hAG 2; HPC8; AGR2
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Species
Mouse
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Source
E. coli
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Tag
C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
NP_035913.1
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Expression Region
K21-L175
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Protein Length
Full Length of Mature Protein
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Molecular Weight
18.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The AG-2 recombinant protein has garnered significant attention in recent years due to its potential applications in various scientific fields, including biotechnology and medicine. Research surrounding AG-2 is primarily motivated by its role in cellular processes and disease mechanisms, particularly in relation to tumor growth, immune response, and genetic regulation. The AG-2 protein is recognized for its involvement in cell signaling pathways, which are crucial for maintaining cellular homeostasis and responding to environmental changes. Investigations into AG-2's structure and function have unveiled its potential as a biomarker for certain cancers, where its expression levels may indicate disease progression or response to treatment. Furthermore, AG-2's stability and ease of production make it an attractive candidate for therapeutic interventions, including drug development and gene therapy. Ongoing studies are focused on elucidating its precise molecular interactions and exploring how modifications to the AG-2 protein could enhance its therapeutic efficacy or reduce side effects. The growing body of research highlights not only the importance of AG-2 in fundamental biology but also its promising role in advancing personalized medicine approaches and improving patient outcomes in various diseases.
