Analytical Data
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Gene name
Serpina5
- Application
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Alternative Names
Plasminogen activator inhibitor 3 Short name: PAI-3 Short name: PAI3 Protein C inhibitor Short name: PCI Serpin A5 Pci
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Species
Mouse
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Source
Baculovirus
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P70458
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Expression Region
25-405aa
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Molecular Weight
45.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Serpina5, also known as corticosteroid-binding globulin (CBG), is a key protein involved in the transport and regulation of corticosteroids in the bloodstream. It plays a crucial role in modulating the bioavailability and activity of these hormones, which are vital for processes such as stress response, metabolism, and immune function. Research on Serpina5 has garnered significant attention due to its implications in various physiological and pathological conditions, such as adrenal disorders, depression, and metabolic syndromes. The study of recombinant Serpina5 protein production has advanced our understanding of its structure-function relationship and potential therapeutic applications. Recombinant technology allows for the generation of large quantities of pure Serpina5, enabling detailed biochemical analyses and the exploration of its interactions with corticosteroids and other proteins. Such studies may lead to the identification of novel therapeutic targets and strategies for diseases associated with corticosteroid dysregulation. By elucidating the mechanisms by which Serpina5 regulates corticosteroid activity, researchers aim to develop better diagnostic tools and treatment options for conditions linked to hormonal imbalances. Overall, the exploration of recombinant Serpina5 presents promising avenues for advancing our understanding of corticosteroid biology and improving clinical outcomes in related disorders.
