Analytical Data
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Gene name
SP-17
- Application
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Alternative Names
Cancer/testis antigen 22 ;CT22Sp17-1Sperm autoantigenic protein 17 ;Sperm protein 17
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15506
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Expression Region
1-146aa
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Molecular Weight
43.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The SP-17 recombinant protein has garnered significant interest in scientific research, particularly in the fields of immunology and reproductive biology. SP-17 is identified as a proliferation-related spermatozoa antigen and is predominantly expressed in the sperm of various species including humans. Its role as a potential target for immunocontraception has spurred investigations into its ability to elicit an immune response. Researchers aim to explore its implications in infertility treatments, vaccine development, and contraceptive strategies. Understanding the molecular structure and function of SP-17 can provide insights into its interactions with the immune system, potentially leading to innovative approaches in reproductive health. The development of SP-17 as a recombinant protein facilitates its purification and characterization, allowing for detailed studies on its immunogenic properties and the mechanisms by which it may evoke antibody production. Moreover, the ongoing exploration of SP-17’s role in sperm motility and fertilization processes highlights its biological significance, suggesting that it could also serve as a biomarker for male fertility assessments. This multifaceted approach to studying SP-17 reinforces its potential applications in both clinical settings and the advancement of reproductive technologies, making it a focal point for further biomedical research.
