Analytical Data
-
Gene name
SUPT5H
- Application
-
Alternative Names
SPT5; SPT5H; DRB sensitivity-inducing factor 160 kDa subunit; DRB sensitivity-inducing factor large subunit; Tat-cotransactivator 1 protein; Transcription elongation factor SPT5
-
Species
Human
-
Source
E. coli
-
Tag
N- His & GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
O00267
-
Expression Region
Asp176~Val270
-
Molecular Weight
41kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SUPT5H, also known as Suppressor of Ty 5 Homolog, is a crucial protein involved in various cellular processes, particularly in the regulation of transcription and RNA processing. As a member of the THO complex, SUPT5H plays a significant role in the coupling between transcription and mRNA export, ensuring that messenger RNA is efficiently processed and transported from the nucleus to the cytoplasm. Dysregulation of SUPT5H has been implicated in several pathological conditions, including cancer and neurological disorders, making it a protein of interest in biomedical research. The study of recombinant SUPT5H protein has garnered attention as researchers aim to elucidate its structural and functional properties, investigate its interactions with other molecular partners, and understand its role in gene expression regulation. By generating recombinant forms of SUPT5H, scientists can perform in-depth biochemical analyses, which are essential for uncovering the protein's mechanisms of action and its involvement in disease. The knowledge gained from these studies could potentially lead to the development of therapeutic strategies targeting SUPT5H-related pathways, highlighting the significance of this protein in both fundamental biology and clinical applications.
