Analytical Data
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Gene name
EN2
- Application
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Alternative Names
AUTS1
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P19622
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Expression Region
Met1~Glu333
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Molecular Weight
40kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EN2 (Engrailed 2) is a transcription factor that belongs to the engrailed gene family, which plays a crucial role in the development and patterning of the central nervous system during embryonic development. Research has highlighted its significance in neurodevelopmental diseases and disorders, particularly in autism spectrum disorders (ASD) and schizophrenia, where altered EN2 expression has been associated with aberrant neural connectivity and behavior. The interest in EN2 is further fueled by its potential therapeutic implications, as understanding its functions and mechanisms might contribute to developing targeted interventions for neurodevelopmental conditions. Additionally, EN2's expression patterns and effects on neuronal differentiation have made it a focus of genetic studies aimed at uncovering the molecular pathways involved in brain development. Recombining EN2 proteins in laboratory settings allows researchers to explore their biochemical properties, binding affinities, and interaction with other cellular proteins, providing valuable insights into its role in neurogenesis. Overall, EN2 recombined protein research bridges fundamental biology with potential clinical applications, emphasizing the gene's importance in understanding both normal and pathological brain development.
