Analytical Data
-
Gene name
LHX1
- Application
-
Alternative Names
LIM1
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P48742
-
Expression Region
Met1~Gln191
-
Molecular Weight
30kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LHX1 (LIM homeobox 1) is a transcription factor that plays a crucial role in neurodevelopment, particularly in the formation of the brain's midline structures and the development of hypothalamic and pituitary tissues. Mutations or dysregulation of LHX1 have been linked to various neurodevelopmental disorders, including defects in the hypothalamus that can lead to hormonal imbalances. Recent studies have highlighted the potential of LHX1 as a target for therapeutic interventions, given its pivotal role in cell fate determination and differentiation during early development. Researchers have focused on producing recombinant LHX1 protein to investigate its functional underpinnings more thoroughly. By expressing and purifying LHX1 protein, scientists aim to elucidate its structural properties and regulatory mechanisms in a cellular context. This recombinant protein study is essential for understanding how LHX1 interacts with other proteins and DNA, thereby influencing gene expression patterns during critical phases of neural development. Further exploration of LHX1 may offer insights into its potential involvement in regenerative medicine and the treatment of developmental disorders, paving the way for novel strategies to mitigate the impacts of neurodevelopmental abnormalities.
