Analytical Data
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Gene name
BAT3
- Application
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Alternative Names
BAG6; Protein G3; Protein Scythe; BCL2-associated athanogene 6; BAG family molecular chaperone regulator 6; Large proline-rich protein BAG6
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Species
Mouse
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Z1R2
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Expression Region
Met1~Ser213
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Molecular Weight
52kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The BAT3 protein, also known as BAT3/SSBP2, is a multifunctional protein that plays a crucial role in various cellular processes, including protein folding, immune response, and apoptosis. It is involved in the quality control of newly synthesized proteins in the endoplasmic reticulum and has been implicated in the regulation of major histocompatibility complex (MHC) class I molecule presentation, thereby influencing T cell activation and immune surveillance. Research into BAT3 has gained momentum due to its association with several diseases, including cancer, where it may contribute to tumor progression and immune evasion. Moreover, its interaction with other proteins and involvement in cellular pathways such as the stress response and autophagy highlight its potential as a therapeutic target. Recent studies have focused on the structural and functional characterization of BAT3, aiming to unravel its complex biological roles and the mechanisms governing its activity. Understanding BAT3's functions and regulation may lead to novel strategies for enhancing immune responses in cancer therapy and improving the effectiveness of vaccines. As research continues to elucidate the network of interactions involving BAT3, it is becoming increasingly clear that this protein could serve as a critical player in maintaining cellular homeostasis and advancing therapeutic approaches in immunology and oncology.
