Analytical Data
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基因名
FITC-Labeled ROBO1
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简介
The ROBO1 protein is a receptor for SLIT1 and SLIT2 and plays a key role in cellular responses during migration, including axonal navigation and projection. Interaction with FLRT3 promotes axonal attraction to NTN1-expressing cells. FITC-Labeled ROBO1 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled ROBO1 protein, expressed by HEK293 , with His labeled tag.
- Application
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别名
ROBO1/DUTT1
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种属
Human
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表达系统
HEK293
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标签
His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y6N7-1
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表达区间
Q26-P897
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蛋白长度
Extracellular Domain
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分子量
110-120 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The ROBO1 protein, a member of the Roundabout (Robo) family of guidance receptors, plays a critical role in neurodevelopment, particularly in axon guidance and cell migration during embryonic development. Research has shown that ROBO1 is implicated in various physiological processes, including neuronal network formation and the regulation of cell signaling pathways. Aberrant expression or malfunction of ROBO1 has been associated with neurological disorders and certain cancers, making it a significant focus of biomedical research. The use of FITC-labeled (fluorescein isothiocyanate) ROBO1 recombinant proteins has emerged as a valuable tool for studying the spatial distribution and functional characteristics of ROBO1 in cellular and tissue contexts. FITC labeling permits the visualization of ROBO1 in real-time using fluorescence microscopy and flow cytometry, enabling researchers to track its localization, interactions with other molecules, and role in cellular processes. This technique is particularly useful in evaluating the effects of various ligands and environmental conditions on ROBO1 function. Overall, the study of FITC-labeled ROBO1 recombinant proteins not only enhances our understanding of the fundamental biology of ROBO1 but also opens avenues for therapeutic interventions in disorders linked to ROBO1 dysregulation.
