Analytical Data
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基因名
HTN1
- Application
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别名
PPB; HIS1; Histidine-rich protein 1; Post-PB protein;
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P15515
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表达区间
Asp20~Asn57
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分子量
15kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HTN1, or Histone H1, is a crucial member of the histone family that plays a significant role in the compaction and organization of eukaryotic DNA within the nucleus. Research on HTN1 recombinant protein has garnered attention due to its implications in chromatin structure and gene regulation. Histone H1 is known to bind to linker DNA between nucleosomes, facilitating higher-order chromatin folding and influencing transcriptional activity. Its dysregulation has been linked to various diseases, including cancer, making it a target of interest for therapeutic interventions. The recombinant expression of HTN1 allows for the detailed study of its biochemical properties, interactions with other nuclear proteins, and its functional role in chromatin dynamics. By producing HTN1 in a controlled laboratory setting, researchers can explore its potential as a biomarker or therapeutic target, as well as unravel the complexities of epigenetic regulation. Understanding the structure and function of HTN1 could provide valuable insights into cellular processes and contribute to the development of novel strategies for disease treatment and prevention.












