Analytical Data
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基因名
OLIG1
- Application
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别名
Class B basic helix-loop-helix protein 6 Short name: bHLHb6 Class E basic helix-loop-helix protein 21 Short name: bHLHe21
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种属
Human
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表达系统
Yeast
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TAK6
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表达区间
17-105aa
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分子量
11.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OLIG1, or oligodendrocyte transcription factor 1, is a crucial protein for the development and differentiation of oligodendrocytes, the myelinating cells in the central nervous system. It plays a significant role in neurodevelopmental processes, influencing myelination and maintaining the integrity of neural circuits. Research into OLIG1 has gained prominence due to its implications in various neurological disorders, such as multiple sclerosis, where demyelination occurs. Understanding the molecular mechanisms by which OLIG1 regulates oligodendrocyte lineage development can provide insights into potential therapeutic strategies aimed at promoting remyelination and repairing damaged neural tissues. Moreover, OLIG1 is involved in the regulation of neuronal survival and repair processes, making it a critical target for studies related to neurodegeneration and brain injuries. The exploration of OLIG1 recombinant proteins allows researchers to investigate its functional characteristics and interactions with other molecular players in the oligodendrocyte lineage. Additionally, studying OLIG1 in various model systems enhances our understanding of its role in health and disease, paving the way for novel approaches in regenerative medicine and targeted therapies for CNS disorders. Thus, the continued investigation of OLIG1 and its recombinant forms is vital for elucidating its contributions to both normal brain function and pathologies associated with oligodendrocyte dysfunction.
