Analytical Data
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Gene name
SLC27A4/FATP4
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简介
The SLC27A4/FATP4 protein centrally regulates cellular processes by regulating the levels of long-chain fatty acids (LCFA), which are critical for their transport across membranes. As the major LCFA transporter in small intestinal enterocytes, it plays a key role in early embryonic fat absorption. SLC27A4/FATP4 Protein, Human (HEK293, His) is the recombinant human-derived SLC27A4/FATP4 protein, expressed by HEK293 , with N-His labeled tag.
- Application
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Alternative Names
Long-chain fatty acid transport protein 4; Arachidonate--CoA ligase; ACSVL4
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Species
Human
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Source
HEK293
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Tag
N-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
Q6P1M0-1
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Expression Region
Q483-L643
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Protein Length
Partial
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Molecular Weight
20-25 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC27A4, also known as FATP4 (fatty acid transport protein 4), is a member of the fatty acid transporter family, which plays a crucial role in the uptake and metabolism of long-chain fatty acids in various tissues. Its expression is particularly prominent in tissues such as the liver, intestine, and adipose tissue, where it regulates lipid homeostasis and energy metabolism. Recent research has highlighted the significance of SLC27A4 in various physiological processes, including insulin sensitivity, inflammation, and cellular signaling pathways. Dysregulation of this fatty acid transporter has been implicated in metabolic disorders such as obesity, type 2 diabetes, and cardiovascular diseases. Studies utilizing recombinant SLC27A4/FATP4 proteins have provided insights into its molecular mechanisms, substrate specificity, and interactions with other cellular components. Understanding the function of SLC27A4 is essential for elucidating its role in metabolic diseases and could lead to the identification of novel therapeutic targets for managing lipid-related disorders. Investigating recombinant forms of this protein enables researchers to explore its physiological and pathological implications in a controlled setting, facilitating the development of potential interventions aimed at restoring fatty acid homeostasis.
