Cat: IPD-X38576

Recombinant Rat NCDN Protein,His

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Analytical Data

  • Gene name

    NCDN

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Norbin

  • Species

    Rat

  • Source

    E. coli

  • Tag

    N-His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O35095

  • Expression Region

    Ser2~Gly300

  • Molecular Weight

    36kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

NCDN (Neurochondrin) is a protein that has garnered significant attention due to its potential role in neuronal development and function. Initially identified in the central nervous system, NCDN is believed to be involved in the regulation of synaptic plasticity, a crucial process for learning and memory. Research has shown that alterations in NCDN expression may be linked to various neurodevelopmental disorders and neurodegenerative diseases, which underscores its importance in neuroscience. The study of recombinant NCDN protein is particularly relevant as it allows for the detailed examination of its structure, function, and interactions with other cellular components. By producing NCDN in a recombinant form, researchers can manipulate its expression levels and investigate its biochemical properties in vitro. This approach facilitates the understanding of the molecular mechanisms underlying NCDN's role in neuronal health, and how disruptions in its function might contribute to disease. Furthermore, recombinant NCDN can be used in therapeutic applications, enabling the development of potential treatments targeting the pathways involved in neurological conditions. Overall, the ongoing research on recombinant NCDN protein represents a promising avenue for advancing our comprehension of neuronal biology and addressing the challenges posed by related pathologies.

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