Analytical Data
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Gene name
PAX2
- Application
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Alternative Names
PAX2; Paired box protein Pax-2
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q02962
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Expression Region
1-388aa
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Molecular Weight
68.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PAX2 is a crucial transcription factor that plays a vital role in the development of the kidneys, eyes, and central nervous system. Mutations in the PAX2 gene are linked to various congenital disorders, including renal agenesis and optic nerve hypoplasia, highlighting its importance in organogenesis and tissue differentiation. The study of PAX2 recombinant proteins has gained significant attention as researchers aim to better understand its functional mechanisms in cellular processes. By producing recombinant PAX2 proteins, scientists can investigate their binding affinities to DNA, interactions with other proteins, and their regulatory roles in gene expression. Additionally, recombinant PAX2 can be utilized in therapeutic applications, potentially leading to novel treatments for PAX2-related conditions. Advances in biotechnology, particularly in protein expression and purification techniques, have facilitated the generation of high-quality recombinant PAX2 proteins for research. Understanding the structure-function relationships of PAX2 through these studies could provide insights into developmental biology and contribute to the development of targeted gene therapies. Overall, the investigation of PAX2 recombinant proteins is essential for elucidating the complexities of organ development and addressing genetic disorders associated with PAX2 mutations.
