Analytical Data
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Gene name
GGACT
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简介
The GGACT protein uses its enzymatic activity to break cross-links between lysine and glutamate residues, actively promoting the degradation of proteins cross-linked by transglutaminase. In addition, GGACT catalyzes the formation of 5-oxo-L-proline from the substrate L-γ-glutamyl-L-ε-lysine. GGACT Protein, Human (HEK293, His) is the recombinant human-derived GGACT protein, expressed by HEK293 , with N-6*His labeled tag.
- Application
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Alternative Names
Gamma-Glutamylaminecyclotransferase; GGACT; AIG2-Like Domain-Containing Protein 1; A2LD1
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Species
Human
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Source
HEK293
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Tag
N-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BVM4
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Expression Region
M1-R153
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Protein Length
Full Length
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Molecular Weight
18 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The GGACT protein, a recombinant protein of significant interest in biochemical and medical research, has gained attention due to its unique structural features and potential applications. It belongs to a class of proteins that display intricate folding patterns, which are crucial for their biological functions. The study of GGACT is rooted in the understanding of protein interactions and their roles in various cellular processes, including signaling, enzymatic activity, and structural support. Advances in genetic engineering techniques have made it feasible to produce GGACT in heterologous systems, allowing researchers to analyze its properties in controlled conditions. This recombinant approach not only facilitates large-scale production but also enables the exploration of post-translational modifications and the investigation of structure-function relationships. Furthermore, GGACT's potential implications in therapeutic applications, including drug design and disease modeling, underscore the importance of this research. Continued exploration of GGACT could provide insights into fundamental biological mechanisms and pave the way for innovative treatments for diseases linked to protein misfolding and dysfunction. As research progresses, the GGACT protein stands as a model for understanding the complexities of protein behavior, offering promising avenues for scientific discovery and technological advancement.
