Analytical Data
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基因名
NT3
- Application
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别名
NTF3; HDNF; NGF2; Nerve Growth Factor 2; Neurotrophic Factor
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种属
Rat
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
-
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表达区间
Thr130~Gly256
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分子量
18kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NT3 (Neurotrophin-3) is a member of the neurotrophin family, which plays a crucial role in the development, maintenance, and survival of neurons. The study of NT3 recombinant proteins has gained significant interest due to their potential therapeutic applications in neurodegenerative disorders, peripheral nerve injuries, and other neurological conditions. NT3 functions primarily by binding to specific receptors, promoting neuron growth and differentiation, and facilitating synaptic plasticity. Researchers have focused on the recombinant expression of NT3 in various systems to enhance its availability for therapeutic use. This involves techniques such as gene cloning, protein expression, and purification, aiming to create biologically active forms of NT3 that can be utilized in experimental and clinical settings. The promise of NT3-based treatments extends to enhancing nerve regeneration and improving outcomes for patients suffering from conditions like spinal cord injuries, Alzheimer’s disease, and other neuropathies. Furthermore, ongoing studies are exploring the signaling pathways activated by NT3 and its interactions with other neurotrophic factors, contributing to a better understanding of its biological mechanisms. Overall, research into NT3 recombinant proteins is paving the way for innovative approaches in regenerative medicine and neurobiology, holding the potential to transform how we treat various neurological ailments.












