Analytical Data
-
基因名
Bcl-2-like 蛋白 11
- Application
-
别名
Bcl2-interacting mediator of cell death
-
种属
Human
-
表达系统
Yeast
-
标签
N- His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O43521
-
表达区间
1-198aa
-
分子量
24.2 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Bcl-2-like protein 11 (Bcl-2L11), also known as Bok, is a member of the Bcl-2 family of proteins, which play critical roles in the regulation of apoptosis, or programmed cell death. This family is divided into pro-apoptotic and anti-apoptotic members, and Bcl-2L11 is primarily characterized as a pro-apoptotic factor. Research has shown that Bcl-2L11 is involved in various cellular processes, including apoptosis, cell cycle regulation, and response to stress. Its expression is often tightly regulated, and dysregulation can lead to various pathological conditions, including cancer, where the evasion of apoptosis is a hallmark of tumor progression. Recombinant Bcl-2L11 protein has gained attention in scientific research due to its potential therapeutic applications and its roles in understanding apoptosis mechanisms. Studies have focused on the structural characterization, functional analysis, and interactions of Bcl-2L11 with other proteins to elucidate its precise role in apoptosis signaling pathways. Moreover, the recombinant form of this protein can be useful in drug discovery and development, particularly in creating new cancer therapies that aim to restore apoptotic pathways in malignant cells. Understanding Bcl-2L11’s functions and mechanisms through recombinant protein research could provide significant insights into cancer biology and lead to innovative strategies for cancer treatment.
