Analytical Data
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基因名
PFDN2
- Application
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别名
PFD2
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q9UHV9
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表达区间
Met1~Ser154
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分子量
20.3kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PFDN2 (Prefoldin-2) is a chaperone protein involved in the assembly and folding of nascent polypeptides. It plays a critical role in the protein maturation process by aiding in the proper folding of newly synthesized proteins, thereby preventing misfolding and aggregation. Research has revealed that PFDN2 is essential in various cellular processes, including stress response, development, and differentiation. It has been implicated in several diseases, including cancer and neurodegenerative disorders, where its dysregulation can lead to protein misfolding and aggregation. The study of recombinant PFDN2 protein serves to elucidate its structural and functional properties, allowing researchers to better understand its mechanism of action and role in cellular homeostasis. By producing PFDN2 in a recombinant system, scientists can obtain large quantities of the protein for biochemical analyses and functional assays. This research is vital not only for exploring the fundamental biology of chaperone proteins but also for developing potential therapeutic strategies targeting PFDN2 in disease contexts. Understanding the interactions of PFDN2 with substrate proteins can provide insights into protein folding pathways, with implications for improving protein stability in therapeutic protein production and designing novel intervention strategies for diseases associated with protein misfolding.












