Analytical Data
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Gene name
TSSK2
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简介
The TSSK2 protein is a testis-specific serine/threonine protein kinase that is indispensable during late spermatogenesis and contributes to cytoplasmic remodeling. It is regulated by phosphorylating “Ser-288” of TSKS and SPAG16. TSSK2 Protein, Human (sf9, GST) is the recombinant human-derived TSSK2 protein, expressed by sf9 insect cells , with N-GST labeled tag.
- Application
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Alternative Names
TSSK2; Testis-specific serine/threonine-protein kinase 2; TSK-2; TSK2; TSSK-2; Testis-specific kinase 2; DiGeorge syndrome protein G; DGS-G; Serine/threonine-protein kinase 22B
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Species
Human
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Source
Baculovirus
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Tag
N-GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96PF2
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Expression Region
D2-T358
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TSSK2 (Testis-Specific Serine Kinase 2) is a member of the serine/threonine kinase family, predominantly expressed in the testes, and plays a crucial role in male fertility. This protein is involved in spermatogenesis, impacting the development and maturation of sperm cells. Research into TSSK2 has gained momentum due to its potential implications in reproductive health and fertility disorders. The regulation and functional mechanisms of TSSK2 are of particular interest, as dysregulation may lead to impaired sperm function and contribute to male infertility. Investigating the biochemical pathways and molecular interactions of TSSK2 could provide insights into its role in spermatogenic processes and highlight its potential as a therapeutic target for infertility treatments. Additionally, the development of recombinant TSSK2 protein in vitro offers opportunities for detailed structural and functional assays, enabling researchers to unravel the specific roles TSSK2 plays within the testes and its impact on sperm quality. Overall, TSSK2 serves as a promising subject for studies aimed at understanding the complexities of male reproductive biology and advancing fertility-related therapies.
