Analytical Data
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Gene name
ULK3
- Application
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Alternative Names
Serine/threonine-protein kinase ULK3; Unc-51-like kinase 3; ULK3; Homo sapiens; Human; Kinase; Serine/threonine-protein kinase; Transferase; 2.7.11.1
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Species
Human
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Source
Baculovirus
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Tag
N-His;N-GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6PHR2-1
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Expression Region
A2-Q472
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Protein Length
Partial
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Molecular Weight
81.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ULK3 (Unc-51 Like Autophagy Activating Kinase 3) is a member of the Unc-51-like kinase family, which plays a pivotal role in the regulation of autophagy, a cellular process essential for maintaining cellular homeostasis, energy balance, and response to stress. Research into ULK3 has gained traction due to its involvement in various physiological and pathological processes, including development, neurodegeneration, cancer, and metabolic diseases. ULK3 is known to participate in the initiation of the autophagic process by phosphorylating key substrates, thereby influencing autophagosome formation. The study of ULK3 recombinant proteins provides significant insights into its structural and functional properties, regulatory mechanisms, and potential as a therapeutic target. By understanding its role in autophagy regulation, researchers are exploring ULK3's implications in disease contexts, including tumorigenesis and neurodegeneration. Furthermore, as a potential biomarker for certain diseases, ULK3 is of considerable interest for drug discovery and development aimed at modulating autophagic processes. Thus, the investigation of ULK3 recombinant proteins serves not only to elucidate its biological functions but also to pave the way for novel therapeutic strategies targeting autophagy-related pathways in human diseases.
