Analytical Data
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基因名
CHRM2
- Application
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别名
Muscarinic acetylcholine receptor M2; CHRM2; Homo sapiens; Human; G-protein coupled receptor; Receptor; Transducer
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种属
Human
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表达系统
E. coli
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标签
N-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P08172
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表达区间
S210-R387
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蛋白长度
Cytoplasmic Domain
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CHRM2, or muscarinic acetylcholine receptor M2, is a member of the G protein-coupled receptor family and plays a critical role in various physiological processes, including modulation of neurotransmitter release and regulation of heart rate. Research into CHRM2 has gained significant interest due to its involvement in cognitive functions and its potential linkage to psychiatric disorders such as anxiety and schizophrenia. Studies have shown that variations in the CHRM2 gene may be associated with alterations in memory performance and susceptibility to mental health issues. The recombinant CHRM2 protein serves as an important tool for understanding the structural and functional characteristics of this receptor. By expressing and purifying CHRM2 in systems such as bacteria or eukaryotic cells, researchers can investigate its binding properties, signaling pathways, and interactions with other proteins. This can further illuminate the receptor's role in cellular signaling and its implications in therapeutic contexts. Additionally, recombinant CHRM2 proteins can be utilized in drug screening assays to identify potential pharmacological agents that modulate receptor activity, paving the way for the development of novel treatments for related disorders. The ongoing research into recombinant CHRM2 thus holds promise for uncovering new insights into neurobiology and developing innovative strategies for addressing mental health challenges.
