Analytical Data
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基因名
SLC15A2
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简介
The SLC15A2 protein is a proton-coupled amino acid transporter that prefers dipeptides and transports oligopeptides containing 2 to 4 amino acids. The stoichiometric ratio of protons to peptides is 2:1 or 3:1, which helps the kidneys absorb dipeptides and tripeptides. SLC15A2 Protein, Human (HEK293, His, MBP, FLAG) is the recombinant human-derived SLC15A2 protein, expressed by HEK293 , with N-MBP, C-Flag, N-8*His labeled tag.
- Application
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别名
SLC15A2; Solute carrier family 15 member 2; Kidney H(+)/peptide cotransporter; Oligopeptide transporter; kidney isoform; Peptide transporter 2
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种属
Human
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表达系统
HEK293
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标签
N-MBP;C-Flag;N-8*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q16348
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表达区间
N2-L729
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC15A2, a member of the solute carrier family, is primarily involved in the transport of peptide-like molecules across cellular membranes. This transporter is critical for nutrient absorption, particularly in the intestinal and renal systems, where it facilitates the uptake of dipeptides and tripeptides derived from dietary proteins. Recent studies have highlighted its role in the modulation of immune responses and its potential significance in various pathophysiological conditions, including metabolic disorders and cancer. Recombination techniques have allowed researchers to produce SLC15A2 recombinant proteins for functional assays, providing insights into its transport mechanisms and substrate specificity. Understanding the structure-functional relationships of SLC15A2 through these recombinant proteins can pave the way for therapeutic interventions targeting nutrient absorption disorders and enhancing drug delivery systems. Furthermore, elucidating its interaction with other cellular pathways may reveal novel strategies for combating diseases related to impaired transportation of essential biomolecules. Given the growing interest in the role of transporters in pharmacokinetics and drug design, the study of SLC15A2 through recombinant protein expression is increasingly pertinent in the field of biomedicine.
