Analytical Data
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Gene name
ZBTB7B
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简介
The ZBTB7B protein is a transcriptional regulator that determines the lineage commitment of T cell precursors, which is critical for the fate of CD4 and CD8 cells. Essential for CD4 commitment, its absence results in CD8 commitment. ZBTB7B Protein, Human (sf9) is the recombinant human-derived ZBTB7B protein, expressed by sf9 insect cells , with tag free.
- Application
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Species
Human
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Source
Baculovirus
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15156
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Expression Region
G2-S539
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Protein Length
Full Length
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZBTB7B, also known as ZNFN1A1 or RBTB1, is a member of the zinc finger and BTB/POZ (Broad-Complex, Tramtrack, and Bric-a-brac/Poxvirus and Zinc-finger) transcription factor family. This protein plays a crucial role in the regulation of gene expression and is involved in various biological processes, including cell differentiation, proliferation, and immune response. Research has indicated that ZBTB7B may act as a tumor suppressor, with alterations in its expression linked to several types of cancers, such as hematological malignancies and solid tumors. Given its significant role in cancer biology, the investigation of ZBTB7B recombinant protein has emerged as a focal point for understanding its molecular functions and interactions. By producing and characterizing recombinant ZBTB7B, researchers aim to elucidate its structural properties, binding affinities, and regulatory mechanisms, which could inform the development of novel therapeutic strategies. This research also holds the potential to identify biomarkers for cancer diagnosis and prognosis, highlighting the importance of ZBTB7B in both basic and applied biomedical research.
