Analytical Data
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基因名
ZBTB7B
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简介
The ZBTB7B protein is a transcriptional regulator that determines the lineage commitment of T cell precursors, which is critical for the fate of CD4 and CD8 cells. Essential for CD4 commitment, its absence results in CD8 commitment. ZBTB7B Protein, Human (sf9) is the recombinant human-derived ZBTB7B protein, expressed by sf9 insect cells , with tag free.
- Application
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种属
Human
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表达系统
Baculovirus
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15156
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表达区间
G2-S539
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蛋白长度
Full Length
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZBTB7B, also known as ZNFN1A1 or RBTB1, is a member of the zinc finger and BTB/POZ (Broad-Complex, Tramtrack, and Bric-a-brac/Poxvirus and Zinc-finger) transcription factor family. This protein plays a crucial role in the regulation of gene expression and is involved in various biological processes, including cell differentiation, proliferation, and immune response. Research has indicated that ZBTB7B may act as a tumor suppressor, with alterations in its expression linked to several types of cancers, such as hematological malignancies and solid tumors. Given its significant role in cancer biology, the investigation of ZBTB7B recombinant protein has emerged as a focal point for understanding its molecular functions and interactions. By producing and characterizing recombinant ZBTB7B, researchers aim to elucidate its structural properties, binding affinities, and regulatory mechanisms, which could inform the development of novel therapeutic strategies. This research also holds the potential to identify biomarkers for cancer diagnosis and prognosis, highlighting the importance of ZBTB7B in both basic and applied biomedical research.
