Analytical Data
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基因名
OSMR beta
- Application
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别名
OSMRB; IL-31RB; Oncostatin-M-specific receptor subunit beta; Interleukin-31 receptor subunit beta
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种属
Mouse
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
O70458
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表达区间
Trp410~Gly652
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分子量
58kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OSMR (oncostatin M receptor) is a member of the cytokine receptor family that is involved in various physiological processes, including hematopoiesis and inflammation. Its ligand, oncostatin M (OSM), plays a significant role in cell signaling pathways that influence cell growth, differentiation, and immune responses. The OSMR beta subunit is particularly important as it forms complexes with other receptor subunits to mediate these signaling effects. Research has shown that OSMR beta is implicated in several pathological conditions, including cancer, where it may contribute to tumor progression and metastasis. Given its crucial role in these biological processes, OSMR beta represents a potential target for therapeutic intervention. To better understand its function and develop strategies for modulation, scientists are focusing on the production of recombinant OSMR beta proteins. These recombinant proteins can be utilized in various applications, including the study of receptor signaling pathways, the development of OSMR-targeted drugs, and the exploration of its role in disease mechanisms. By characterizing the properties and functions of OSMR beta through recombinant technology, researchers aim to uncover insights that could lead to novel therapeutic approaches for diseases associated with aberrant OSM signaling.
