Analytical Data
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基因名
GALNT13
- Application
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别名
GALNT13; KIAA1918Polypeptide N-acetylgalactosaminyltransferase 13; EC 2.4.1.41; Polypeptide GalNAc transferase 13; GalNAc-T13; pp-GaNTase 13; Protein-UDP acetylgalactosaminyltransferase 13; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IUC8
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表达区间
1-556aa
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氨基酸序列
MRRSVYCKVVLATSLMWVLVDVFLLLYFSECNKCDDKKERSLLPALRAVISRNQEGPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKNLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIPRRYYSLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTDDLCLDVSRLNGPVIMLKCHHMRGNQLWEYDAERLTLRHVNSNQCLDEPSEEDKMVPTMQDCSGSRSQQWLLRNMTLGT
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分子量
90.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GALNT13, a member of the glycosyltransferase family, plays a crucial role in the modification of glycoproteins and proteoglycans by adding N-acetylgalactosamine residues, a process known as O-glycosylation. Research has highlighted its significance in various physiological processes, including cell signaling, development, and immune response. Abnormal GALNT13 activity is linked to several diseases, notably cancer, where altered glycosylation patterns can influence tumor progression and metastasis. Studies have shown that GALNT13 may affect cell adhesion and migration, important factors in cancer biology. Moreover, its expression levels can serve as potential biomarkers for certain malignancies. To further understand GALNT13's function and therapeutic potential, researchers are focusing on the production of recombinant GALNT13 proteins. This approach allows for detailed structural and functional analyses, enabling the exploration of its catalytic mechanisms and interactions with other cellular components. By using recombinant GALNT13, scientists aim to develop targeted therapies that could modulate glycosylation patterns, paving the way for novel treatment strategies in diseases where GALNT13 is implicated. Overall, the study of recombinant GALNT13 protein is positioned at the intersection of basic research and translational medicine, offering insights into both fundamental biological processes and potential clinical applications.
