Analytical Data
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Gene name
FOXG1C
- Application
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Alternative Names
BF-1; BF-2; BF1; BF2; Brain factor 1; Brain factor 2; FHKL; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; Forkhead box protein G1; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead like 1; Forkhead like 2; Forkhead like 3; Forkhead like 4; Forkhead-related protein FKHL1; Forkhead-related protein FKHL2; Forkhead-related protein FKHL3; FOXG1; FOXG1_HUMAN; FOXG1A; FOXG1B; FOXG1C
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P55316
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Expression Region
1-489aa
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AA Sequence
MLDMGDRKEV KMIPKSSFSI NSLVPEAVQN DNHHASHGHH NSHHPQHHHH HHHHHHHPPP PAPQPPPPPQ QQQPPPPPPP APQPPQTRGA PAADDDKGPQ QLLLPPPPPP PPAAALDGAK ADGLGGKGEP GGGPGELAPV GPDEKEKGAG AGGEEKKGAG EGGKDGEGGK EGEKKNGKYE KPPFSYNALI MMAIRQSPEK RLTLNGIYEF IMKNFPYYRE NKQGWQNSIR HNLSLNKCFV KVPRHYDDPG KGNYWMLDPS SDDVFIGGTT GKLRRRSTTS RAKLAFKRGA RLTSTGLTFM DRAGSLYWPM SPFLSLHHPR ASSTLSYNGT TSAYPSHPMP YSSVLTQNSL GNNHSFSTAN GLSVDRLVNG EIPYATHHLT AAALAASVPC GLSVPCSGTY SLNPCSVNLL AGQTSYFFPH VPHPSMTSQS STSMSARAAS SSTSPQAPST LPCESLRPSL PSFTTGLSGG LSDYFTHQNQ GSSSNPLIH
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Molecular Weight
52.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FOXJ2 (Forkhead Box J2) is a member of the forkhead box (FOX) family of transcription factors known for their roles in various biological processes, including development, differentiation, and cellular response to stress. Research into FOXJ2 has gained momentum due to its significant involvement in cilia formation and function, which are critical for proper cellular signaling and movement, particularly in respiratory epithelial cells. Abnormalities in cilia have been linked to diseases such as situs inversus, primary ciliary dyskinesia, and various respiratory illnesses. Given its pivotal role in regulating genes associated with ciliary structure and motility, FOXJ2 is considered a potential therapeutic target for such conditions. Additionally, studies have suggested that FOXJ2 may influence stem cell pluripotency and differentiation, thereby contributing to tissue regeneration and repair. The generation of recombinant FOXJ2 protein allows for in-depth studies of its functional mechanisms, interactions with other proteins, and its impact on ciliary biology, ultimately aiding in the understanding of its role in health and disease. As a result, FOXJ2 stands out as a focus of interest in developmental biology and medical research, as further elucidation of its pathways could lead to novel strategies for treating ciliary-related disorders and enhancing regenerative medicine.
