Analytical Data
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基因名
TAAR2
- Application
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别名
TAAR2；GPR58；Trace amine-associated receptor 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9P1P5
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表达区间
1-351aa
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氨基酸序列
MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TAAR2 (Trace Amine-Associated Receptor 2) belongs to a family of orphan G protein-coupled receptors (GPCRs) that have gained attention for their role in neurotransmission and neurobiology. These receptors are activated by trace amines, which are endogenous compounds that influence various physiological processes, including mood regulation and sensory perception. Research has shown that TAAR2 is expressed in the central nervous system, particularly in regions associated with olfactory processing, suggesting its potential involvement in processing environmental cues and modulating behavioral responses. The characterization of TAAR2 as a receptor responsible for detecting trace amines opens new avenues for understanding neurochemical pathways and their implications in psychiatric disorders. Given the increasing recognition of the role of trace amines and their receptors in neuropsychology, there is significant interest in the functional characterization and potential therapeutic applications of TAAR2. Recent studies have aimed at expressing and purifying TAAR2 recombinant proteins to facilitate binding assays, structural analysis, and pharmacological profiling. Understanding the molecular mechanisms of TAAR2 activation and its downstream signaling pathways could provide insights into the development of novel treatments for mood disorders and other neuropsychiatric conditions, highlighting the importance of TAAR2 in both basic and translational neuroscience research.
