Analytical Data
-
基因名
TFDP1
- Application
-
别名
TFDP1；DP1；Transcription factor Dp-1
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q14186
-
表达区间
2-410aa
-
氨基酸序列
AKDAGLIEA NGELKVFIDQ NLSPGKGVVS LVAVHPSTVN PLGKQLLPKT FGQSNVNIAQ QVVIGTPQRP AASNTLVVGS PHTPSTHFAS QNQPSDSSPW SAGKRNRKGE KNGKGLRHFS MKVCEKVQRK GTTSYNEVAD ELVAEFSAAD NHILPNESAY DQKNIRRRVY DALNVLMAMN IISKEKKEIK WIGLPTNSAQ ECQNLEVERQ RRLERIKQKQ SQLQELILQQ IAFKNLVQRN RHAEQQASRP PPPNSVIHLP FIIVNTSKKT VIDCSISNDK FEYLFNFDNT FEIHDDIEVL KRMGMACGLE SGSCSAEDLK MARSLVPKAL EPYVTEMAQG TVGGVFITTA GSTSNGTRFS ASDLTNGADG MLATSSNGSQ YSGSRVETPV SYVGEDDEED DDFNENDEDD
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TFDP1, or Transcription Factor Dp-1, is a crucial protein that plays a significant role in the regulation of gene expression and cellular proliferation by functioning as a dimerization partner for the E2F transcription factors. These E2F factors are pivotal in controlling the cell cycle, particularly in the transition from the G1 to S phase, thus influencing cell growth and division. The TFDP1 protein interacts with various E2F family members, enhancing their ability to activate target genes involved in cell cycle progression and DNA synthesis. Dysregulation of TFDP1 and its associated pathways is implicated in various cancers, as aberrant E2F activity can lead to uncontrolled cell proliferation. Consequently, understanding the structure, function, and regulatory mechanisms of TFDP1 not only sheds light on fundamental biological processes but also holds potential for therapeutic interventions in cancer treatment. Ongoing research aims to delineate its interactions, post-translational modifications, and role within the broader context of transcriptional regulation, with the hope of elucidating new targets for cancer therapy and advancing our knowledge of cell cycle regulation.
