Analytical Data
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基因名
ZSCAN4
- Application
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别名
Zinc finger and SCAN domain-containing protein 4. Zinc finger protein 494
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NAM6
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表达区间
1-433 aa
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氨基酸序列
MALDLRTIFQCEPSENNLGSENSAFQQSQGPAVQREEGISEFSRMVLNSFQDSNNSYARQELQRLYRIFHSWLQPEKHSKDEIISLLVLEQFMIGGHCNDKASVKEKWKSSGKNLERFIEDLTDDSINPPALVHVHMQGQEALFSEDMPLRDVIVHLTKQVNAQTTREANMGTPSQTSQDTSLETGQGYEDEQDGWNSSSKTTRVNENITNQGNQIVSLIIIQEENGPRPEEGGVSSDNPYNSKRAELVTARSQEGSINGITFQGVPMVMGAGCISQPEQSSPESALTHQSNEGNSTCEVHQKGSHGVQKSYKCEECPKVFKYLCHLLAHQRRHRNERPFVCPECQKGFFQISDLRVHQIIHTGKKPFTCSMCKKSFSHKTNLRSHERIHTGEKPYTCPFCKTSYRQSSTYHRHMRTHEKITLPSVPSTPEAS
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分子量
75.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZSCAN4 is a member of the Zink finger and SCAN domain-containing gene family, playing a crucial role in early embryonic development and stem cell biology. Research into ZSCAN4 has gained significant attention due to its unique expression patterns in pluripotent stem cells and its association with somatic cell reprogramming. The protein is particularly interesting because it has been shown to enhance the efficiency of induced pluripotent stem cell (iPSC) generation, making it a pivotal factor in regenerative medicine and biotechnology. Furthermore, ZSCAN4 exhibits essential functions in maintaining genomic integrity by regulating telomere length and DNA repair mechanisms. This suggests that ZSCAN4 may be integral not only to development but also to the longevity and stability of stem cells. The study of ZSCAN4 recombinant protein offers insights into its biochemical properties and potential applications in cell therapy and tissue engineering. As research progresses, the elucidation of ZSCAN4's molecular mechanisms and interactions could pave the way for novel therapeutic strategies aimed at combating age-related ailments and enhancing cell reprogramming efficiency. Thus, the exploration of ZSCAN4 presents a promising frontier in the fields of developmental biology and regenerative medicine, with implications for improving therapeutic outcomes in various diseases.
