Cat: PAX2000-12324

Recombinant Human UBFD1 Protein,His

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Analytical Data

  • 基因名

    UBFD1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Ubfd1; UBFD1_HUMAN; Ubiquitin domain-containing Protein UBFD1; Ubiquitin-binding Protein homolog; UBPH

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O14562

  • 表达区间

    1-309 aa

  • 氨基酸序列

    MAAAGAPDGM EEPGMDTEAE TVATEAPARP VNCLEAEAAA GAAAEDSGAA RGSLQPAPAQ PPGDPAAQAS VSNGEDAGGG AGRELVDLKI IWNKTKHDVK FPLDSTGSEL KQKIHSITGL PPAMQKVMYK GLVPEDKTLR EIKVTSGAKI MVVGSTINDV LAVNTPKDAA QQDAKAEENK KEPLCRQKQH RKVLDKGKPE DVMPSVKGAQ ERLPTVPLSG MYNKSGGKVR LTFKLEQDQL WIGTKERTEK LPMGSIKNVV SEPIEGHEDY HMMAFQLGPT EASYYWVYWV PTQYVDAIKD TVLGKWQYF

  • 分子量

    33.3  kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

UBFD1, or Ubiquitin-Complementation Factor D1, is a vital protein that plays a crucial role in regulating various cellular processes, including protein degradation and cell signaling. The study of UBFD1 has gained momentum due to its involvement in the ubiquitin-proteasome system, which is essential for maintaining cellular homeostasis and modulating the immune response. Recent research highlights its significance in various diseases, including cancer and neurodegenerative disorders, where dysregulation of protein degradation pathways can lead to the accumulation of misfolded proteins and subsequent cellular dysfunction. Understanding the structure and function of UBFD1 can provide insights into its specific roles in these pathological conditions and open avenues for targeted therapeutic interventions. The recombinant expression of UBFD1 allows for detailed biochemical and biophysical characterization, which is crucial for elucidating its mechanisms and interactions with other cellular components. As the landscape of protein research continues to evolve, UBFD1 represents a promising target for developing innovative treatments that harness the power of modulating protein homeostasis and restoring normal cellular function. This makes UBFD1 a focal point in both basic and translational research, with the potential for significant implications in improving clinical outcomes for various diseases.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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