Analytical Data
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Gene name
UBADC1
- Application
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Alternative Names
UBAC1; GBDR1; KPC2; UBADC1; Ubiquitin-associated domain-containing Protein 1; UBA domain-containing Protein 1; E3 ubiquitin-Protein ligase subunit KPC2; Glialblastoma cell differentiation-related Protein 1; Kip1 ubiquitination-promoting complex Protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BSL1
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Expression Region
1-405 aa
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AA Sequence
MFVQEEKIFAGKVLRLHICASDGAEWLEEATEDTSVEKLKERCLKHCAHGSLEDPKSITHHKLIHAASERVLSDARTILEENIQDQDVLLLIKKRAPSPLPKMADVSAEEKKKQDQKAPDKEAILRATANLPSYNMDRAAVQTNMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDEAALRQLTEMGFPENRATKALQLNHMSVPQAMEWLIEHAEDPTIDTPLPGQAPPEAEGATAAASEAAAGASATDEEARDELTEIFKKIRRKREFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDKGIDPDSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT
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Molecular Weight
45.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UBADC1, a member of the UBAC (Ubiquitin-Associated and C-Terminal Domain) protein family, has garnered increasing attention in recent years due to its potential roles in cellular processes such as protein degradation, stress responses, and cell signaling. Recent studies suggest that UBADC1 may be involved in the regulation of ubiquitin-mediated pathways, highlighting its significance in maintaining cellular homeostasis and influencing various diseases, including cancer and neurodegenerative disorders. The protein’s structure, characterized by its unique C-terminal domain, suggests potential interactions with other ubiquitin-related proteins, creating a complex network crucial for cellular function. Furthermore, preliminary research indicates that alterations in UBADC1 expression or function could contribute to the pathophysiology of certain conditions, offering avenues for therapeutic exploration. Understanding the detailed mechanisms of UBADC1's action and its implications in disease could pave the way for novel biomarker identification and targeted treatments, underscoring the urgency of advancing research in this area. As such, the study of UBADC1 recombinant protein is essential to decipher its biological roles and therapeutic potential, making it a focal point of ongoing research endeavors in molecular biology and biomedical science.
