Analytical Data
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基因名
Nesp1
- Application
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别名
Nesp1;NEDD8-specific protease 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NF91
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Nesp1, or novel extracellular matrix protein 1, has garnered significant interest in biomedical research due to its potential role in various physiological and pathological processes. Initially identified for its involvement in bone development and mineralization, Nesp1 has been shown to regulate cellular activities such as proliferation, differentiation, and matrix deposition. Its unique structural features and expression patterns suggest that it may act as a key player in the extracellular matrix, influencing tissue homeostasis and repair. Recent studies have highlighted Nesp1's interactions with signaling pathways related to bone metabolism, making it a candidate for investigating disorders like osteoporosis and other skeletal conditions. Furthermore, its potential implications in cancer biology and regenerative medicine are also being explored, as the modulation of extracellular matrix components is crucial for tumor progression and tissue regeneration. As a recombinant protein, Nesp1 offers a valuable tool for elucidating its biological functions and therapeutic potential, paving the way for future investigations aimed at leveraging its properties for clinical applications. Understanding Nesp1's mechanisms of action could lead to novel strategies for treating degenerative diseases and enhancing tissue repair, making it a critical focus in protein engineering and regenerative medicine.












