Analytical Data
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Gene name
FCHSD1
- Application
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Alternative Names
FCH and double SH3 domains 1; FCH and double SH3 domains protein 1; FCHSD 1; FCHSD1; FCSD1_HUMAN; FLJ00007 ; Nervous wreck homolog 2; NWK 2; NWK2
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86WN1
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Expression Region
1-409aa
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AA Sequence
MDSRTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTGRSAKEQVLRKGTENLQRAQAEVLQSVRELSRSRKLYGQRERVWALAQEKAADVQARLNRSDHGIFHSRTSLQKLSTKLSAQSAQYSQQLQAARNEYLLNLVATNAHLDHYYQEELPALLKALVSELSEHLRDPLTSLSHTELEAAEVILEHAHRGEQTTSQVSWEQDLKLFLQEPGVFSPTPPQQFQPAGTDQVCVLEWGAEGVAGKSGLEKEVQRLTSRAARDYKIQNHGHRVLQRLEQRRQQASEREAPSIEQRLQEVRESIRRAQVSQVKGAARLALLQGAGLDVERWLKPAMTQAQDEVEQERRLSEARLSQRDLSPTAEDAELSDFEECEETGELFEEPAPQALATRALPCPAHVVFRYQGVRMS
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Molecular Weight
70.73 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FCHSD1, or FCH and double SH3 domain-containing protein 1, is a member of the FCHSD protein family that plays a pivotal role in various cellular processes, including endocytosis and cytoskeleton organization. Recent studies have highlighted its significance in mediating protein-protein interactions and regulating signaling pathways, which are critical for cell adhesion, migration, and proliferation. Given its involvement in these fundamental biological processes, FCHSD1 has garnered attention in cancer research, where its expression levels and functional alterations have been linked to tumor progression and metastasis. Moreover, aberrations in the function of FCHSD1 may contribute to other diseases, emphasizing the necessity for a deeper understanding of its molecular mechanisms. Researchers aim to produce recombinant FCHSD1 proteins to facilitate structural and functional studies, enabling comprehensive investigations into its role in health and disease. The recombinant proteins allow for the exploration of binding affinities, interaction partners, and the biochemical pathways influenced by FCHSD1. Overall, the study of FCHSD1 represents a promising avenue for elucidating its biological significance and potential as a therapeutic target in various diseases, particularly in the context of cancer biology.
