Analytical Data
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Gene name
ZNF669
- Application
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Alternative Names
ZNF669; Zinc finger Protein 669
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96BR6
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Expression Region
1-464 aa
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AA Sequence
MVSGLRLASRSGEEGWLKPAVARLGPPRHRLRNLRTESPWRSRGSVLFCSGPGRAGRAAEPLHPVCTCGRHFRRPDPCREPLASPIQDSVAFEDVAVNFTQEEWALLDSSQKNLYREVMQETCRNLASVGSQWKDQNIEDHFEKPGKDIRNHIVQRLCESKEDGQYGEVVSQIPNLDLNENISTGLKPCECSICGKVFVRHSLLNRHILAHSGYKPYGEKQYKCEQCGKFFVSVPGVRRHMIMHSGNPAYKCTICGKAFYFLNSVERHQRTHTGEKPYKCKQCGKAFTVSGSCLIHERTHTGEKPYECKECGKTFRFSCSFKTHERTHTGERPYKCTKCDKAFSCSTSLRYHGSIHTGERPYECKQCGKAFSRLSSLCNHRSTHTGEKPYECKQCDQAFSRLSSLHLHERIHTGEKPYECKKCGKAYTRSSHLTRHERSHDIEAGCSDSACNPSTLGGQGVWIA
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Molecular Weight
78.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF669, a member of the zinc finger protein family, has garnered attention due to its potential roles in gene regulation and cellular processes. Zinc finger proteins are characterized by their ability to bind DNA, RNA, or proteins, often influencing transcriptional regulation. The ZNF669 gene, located on chromosome 19, is believed to play a crucial role in developmental biology and may be involved in various physiological and pathological processes. Recent studies indicate that alterations in the expression or function of ZNF669 could be linked to several human diseases, including cancer and developmental disorders. Moreover, the increasing interest in precision medicine highlights the need for understanding the specific molecular mechanisms through which ZNF669 operates. Research into the recombinant production of ZNF669 protein aims to elucidate its structure-function relationship and interactions with other molecules. By producing this protein in a recombinantly, scientists can conduct detailed biochemical and biophysical studies, paving the way for potential therapeutic applications and providing insights into its biological significance. The advancement in techniques such as CRISPR and RNA sequencing further emphasizes the importance of understanding ZNF669's role in gene regulation, making it a critical target for future research endeavors.
