Analytical Data
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Gene name
ZNF645
- Application
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Alternative Names
CBLL2; ZNF645E3 ubiquitin-Protein ligase CBLL2; EC 2.3.2.27; Cbl proto-oncogene-like Protein 2; RING-type E3 ubiquitin transferase ZNF645; Zinc finger Protein 645; c-Cbl-like Protein 2
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N7E2
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Expression Region
1-425 aa
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AA Sequence
MNKMPAGEQECEYNKEGKYYSKGVKLVRKKKKIPGYRWGDIKINIIGEKDDLPIHFCDKCDLPIKIYGRIIPCKHAFCYHCANLYDKVGYKVCPRCRYPVLRIEAHKRGSVFMCSIVQQCKRTYLSQKSLQAHIKRRHKRARKQVTSASLEKVRPHIAPPQTEISEIPKRLQDRDHLSYIPPEQHTMVSLPSVQHMLQEQHNQPHKDIQAPPPELSLSLPFPIQWETVSIFTRKHGNLTVDHIQNNSDSGAKKPTPPDYYPECQSQPAVSSPHHIIPQKQHYAPPPSPSSPVNHQMPYPPQDVVTPNSVRSQVPALTTTYDPSSGYIIVKVPPDMNSPPLRAPQSQNGNPSASEFASHHYNLNILPQFTENQETLSPQFTQTDAMDHRRWPAWKRLSPCPPTRSPPPSTLHGRSHHSHQRRHRRY
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Molecular Weight
46.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF645 (Zinc Finger Protein 645) is a member of the zinc finger protein family, which plays crucial roles in various biological processes, including gene regulation, cell differentiation, and development. Recent studies have highlighted its involvement in key cellular functions and disease mechanisms, particularly in cancer and genetic disorders. Researchers have been activating interest in ZNF645 due to its potential as a biomarker or therapeutic target in oncology and regenerative medicine. The ability to produce recombinant ZNF645 protein has advanced our understanding of its structural and functional properties, facilitating studies on its interactions with other proteins and DNA. Furthermore, the recombinant form can be utilized in high-throughput screening assays to identify small molecules that modulate its activity, opening new avenues for drug discovery. As the functional roles of ZNF645 become increasingly elucidated, the demand for its recombinant protein in research is expected to grow, providing insights into its contribution to cellular processes and potential translational applications in treating various diseases.
